Carnegie Mellon · Foundations of Brain & Behavior · Fall 2026

Foundations of Brain & Behavior, taught properly

Every lecture and study guide so far — rebuilt with intuition, the mechanism drawn out, interactive figures you can break, and exam-shaped problems with the steps hidden until you want them. Built for Midterm 1.

Why this exists

The slides are mostly pictures with labels, and the study guides are lists of terms. Neither shows you why Parkinson's reduces movement while Huntington's increases it, why the Hermann grid has grey dots, or why a double dissociation rules out a serial model. Several exit-ticket questions ("how would you test this?", "why does the scene move the other way?") are asked and never answered.

This guide answers all of them. Every chapter starts from something concrete, gives the mechanism a figure you can play with, states the definitions precisely, and ends with quizzes whose wrong answers are the common misconceptions. Where the study guide and the slides disagree, it says so.

The midterm

DateLectureIn this guide
8/241 · Course introCh. 1
8/262 · Neuroanatomy & neurophysiologyCh. 2, Ch. 3
8/313 · Brain dissection, Marr, TinbergenCh. 3, Ch. 4
9/24 · Dysfunctional brain ICh. 4, Ch. 5
9/95 · Dysfunctional brain IICh. 6, Ch. 7
9/146 · Imaging & perturbing the brainCh. 7, Ch. 8
9/167 · Vision ICh. 8, Ch. 9
9/218 · Vision IICh. 10, Ch. 11
9/239 · Vision IIICh. 11, Ch. 12
9/2810 · Vision IV — colour & the two pathwaysCh. 13
9/3011 · NeuroAI (guest: Dr. Maggie Henderson)Ch. 14
10/512 · Hearing & soundCh. 15
—Speech, music & languageAfter the midterm — not in scope
10/7Midterm exam (25% of the grade)
Practice

Midterm practice

Exam-shaped problems mixing chapters: every study-guide "benefits and limitations" question, dissociation tables, lesion localization, basal-ganglia cases, and vision mechanisms.

Review

One-page cheat sheet

Every definition, pathway and number from Lectures 1–9, compressed. For checking yourself the night before — not for learning from.

Part I — Foundations

Chapter 1

Why study brain & behavior

Change blindness and Shepard's tone (both runnable), the five reasons, the three disciplines, a lesionable dual-route reading model, and why active learning feels worse but works better.

Chapter 2

Neurons, spikes & synapses

Cell and neuron types, an action-potential simulator that shows frequency coding, a synapse you can dose with Parkinson's and depression drugs, and the three kinds of plasticity.

Chapter 3

Organizing & dissecting the brain

The six cortical layers (with the L3 correction), directions and planes you can slice, the four ways to divide the brain, meninges and the dissection views.

Chapter 4

Marr, Tinbergen & representations

Three levels and four questions with worked examples, a paintable Sobel edge detector, the paper-folding and mountain-climber problems, mental rotation, and the priming demos.

Part II — The dysfunctional brain

Chapter 5

Neuropsychology & dissociations

Controls, ceiling and floor effects (with a slider that hides a real deficit), single vs double dissociation, and exactly why the double one rules out a serial model.

Chapter 6

Stroke, aphasia & head trauma

Arterial territories, vessel failures, ischemic vs hemorrhagic stroke, Broca's vs Wernicke's, coup–contrecoup vs diffuse axonal injury, and CTE.

Chapter 7

Neurodegeneration & basal ganglia

A delayed-feedback model of ataxia, a go/no-go circuit simulator for Parkinson's, L-dopa, DBS and Huntington's, and Alzheimer's memory dissociations.

Part III — Methods

Chapter 8

Imaging & perturbing: faces

Behavior, fMRI, EEG/MEG, ECoG, sEEG, patients and stimulation — each through the face question it answers, with a clickable spatial/temporal resolution map.

Part IV — Vision

Chapter 9

The eye, retina & pathway

Camera obscura tradeoffs, rods and cones, the blind spot, Troxler fading, and a lesion simulator for every point from retina to V1.

Chapter 10

LGN, V1 & receptive fields

Magno vs parvo, V1's four properties, a live center–surround cell, the Hermann grid computed, orientation tuning and a population model of tilt adaptation.

Chapter 11

Surfaces & depth

Border ownership, a Kanizsa triangle you can break, seven pictorial cues you switch on one at a time, the Ames room, vergence and disparity.

Chapter 12

Motion

Apparent motion, segmentation by motion, a point-light walker, optic flow, MT/V5 evidence from four methods, and a real motion aftereffect.

Chapter 13

Colour, V4 & the two pathways

Trichromacy and cone types, colour opponency, why illumination makes colour ambiguous, cerebral achromatopsia, and the dorsal/ventral double dissociation (patient DF vs optic ataxia).

Chapter 14

Encoding, decoding & CNNs

Which way each model predicts, what a voxel is and isn't, convolution and kernels, layer-to-area correspondence, stimulus optimization, BCIs, and the ethics of brain decoding.

Chapter 15

Hearing & sound

Cochlea to A1, tonotopy as a place code, sound constancy as the same inference problem as colour constancy, prediction in audition, and how to read a spectrogram.

How to use this guide

The callouts mean something:

Key idea The one thing to remember from a section.
Common mistake A trap — or a place where the slides and study guide disagree.
Intuition The why behind a rule.

going deeper marks material beyond the lectures — good for understanding, unlikely to be tested directly.

A plan for the 11 days before 10/7:

  1. One chapter a session. Do the quizzes before rereading anything.
  2. Play with each figure until you can predict what it'll do before you move the slider.
  3. Do Midterm practice closed-book; revisit the chapters behind anything you missed.
  4. Add Lectures 10–12 as they happen.
  5. Night before: the cheat sheet only.

Figures marked "reconstruction" or "schematic" were rebuilt because the slide images didn't survive text extraction — check them against the original slides before trusting exact details.